Size does matter: VWF in MI.
نویسندگان
چکیده
In this issue of Blood, 2 independent studies analyzed the relevance of the von Willebrand factor (VWF)–ADAMTS13 axis in a murine model of myocardial ischemia/reperfusion injury. It is demonstrated that genetic ablation, neutralization or increased cleavage of VWF is protective in this experimental setting.1,2 This strongly supports the concept that interference with the ADAMTS13-VWF axis may be a powerful approach to treat acute thrombo-inflammatory disease states.
منابع مشابه
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عنوان ژورنال:
- Blood
دوره 120 26 شماره
صفحات -
تاریخ انتشار 2012